Hotel Plaza San Francisco is located in the central part of the city, making it perfect for exploring Santiago on foot or by transit. Guests appreciated the close proximity to the main attractions, access to the metro and being right next door to the oldest church in the city. The location was described as great, excellent, wonderful and perfect for tourists. Some guests did mention that the neighborhood was affected by recent crime and safety concerns at night. However, the central location with basement parking and attentive staff made up for it. There were limited dining options at night in the area, but overall the location was very good, especially for centro historico. The hotel is well-located for visiting museums, restaurants and key landmarks. Despite the recent city developments, the location is still described as central and close to everything downtown, stores, markets and restaurants.